A new mathematical model for the interaction of bacteria in the gut could help design new probiotics and specially tailored diets to prevent diseases. The research is described in "CODY Enables Quantitatively Spatiotemporal Predictions on In Vivo Gut Microbial Variability Induced by Diet Intervention," published in the Proceedings of the National Academy of Sciences.
The paper describes how the mathematical model performed when making predictions involving regular measurements of health indicators, which the researchers compared with the predictions made from their mathematical model. The model's predictions proved to be reliably accurate.
The results "could enable computer-based design for a very complex system," says Jens Nielsen, Professor of Systems Biology at Chalmers University of Technology. "Our model could therefore be used to for creating personalized healthy diets, with the possibility to predict how adding specific bacteria as novel probiotics could impact a patient's health."
From Chalmers University of Technology
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