Communications of the ACM
Nih Research Model Predicts Weight With Varying Diet, Exercise Changes
Kevin Hall of NIH's National Institute of Diabetes and Digestive and Kidney Diseases
Credit: Courtesy of NIH
Researchers at the U.S. National Institutes of Health (NIH) have developed a computer simulation of metabolism that enables scientists to better understand how diet and exercise impact metabolism and ultimately lead to changes in weight and body fat.
The researchers developed a mathematical model to create the simulation tool, which accurately predicts how body weight will change and how long it will likely take to reach weight goals based on one's starting weight and estimated physical activity. The online tool can simulate changes in calories or exercise that would never be recommended for healthy weight loss.
"This research helps us understand why one person may lose weight faster or slower than another, even when they eat the same diet and do the same exercise," says Kevin Hall at NIH's National Institute of Diabetes and Digestive and Kidney Diseases. "Our computer simulations can then be used to help design personalized weight management programs to address individual needs and goals."
A more comprehensive mathematical model of human metabolism was recently used to design an NIH clinical trial that is comparing the effects of reducing fats versus carbohydrates in obese adults.
From NIH News
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