Researchers at the Max Delbruck Center for Molecular Medicine in Germany have developed software to help make sense of vast datasets generated by modern light microscopy of biological tissues.
MDC's Stephan Preibisch and colleagues created BigStitcher software, which can reconstruct and scale the data obtained by light-sheet microscopy, without need for a supercomputer. "One can not only get an overview of the big picture, but can also zoom in to specifically examine individual structures at the desired resolution," Preibisch says.
BigStitcher also can automatically evaluate data quality, and allows users to spin and turn a captured image in any direction. Preibisch adds that the freely-available software can run on any standard computer, which "allows the data to be easily shared across research teams."
From Max Delbruck Center for Molecular Medicine
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Abstracts Copyright © 2019 SmithBucklin, Washington, DC, USA
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