Communications of the ACM
3D-Printed Acoustic Holograms Against Alzheimer's or Parkinson's
The acoustic holograms allow for a more controlled opening of the blood brain barrier than can be achieved by exclusively making use of ultrasound.
Credit: Universitat Politecnica de Valencia (Spain)
A team of researchers at Spain's Universitat Politècnica de València (UPV), the Spanish National Research Council, and Columbia University has created customizable, three-dimensionally-printed acoustic holograms that could be used to treat diseases like Alzheimer's and Parkinson's.
The holograms focus ultrasound to open the blood-brain barrier in a controlled manner, so drugs that target central nervous system-affecting pathologies can pass through.
They also correct for skull-induced aberrations, and can produce an ultrasonic multi-focal beam in critical brain structures.
UPV's Noé Jiménez said the ultrasonic beam "focuses and adapts bilaterally and very precisely on parts of the brain that are of great therapeutic interest.”
From Universitat Politecnica de Valencia (Spain)
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