Communications of the ACM
Zooming In to Get the Full Picture
A new atlas that maps the continuum of embryo development in fruit flies allows scientists to ‘zoom in’ on specific single-cell embryology of the fruit fly.
Credit: Isabel Romero Calvo/EMBL
Scientists at the European Molecular Biology Laboratory and the University of Washington (UW) have built the most comprehensive single-cell map of embryo development in any animal to date, using the fruit fly (Drosophila melanogaster) as its model.
The researchers profiled open chromatin from nearly 1 million cells and RNA from 500,000 cells from overlapping time-points encompassing fruit fly embryogenesis.
Said UW's Diego Calderon, who taught a neural network to predict the developmental time for each cell, "This method allows you to zoom in to any part of this embryogenesis timeline at a scale of minutes."
From European Molecular Biology Laboratory
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Abstracts Copyright © 2022 SmithBucklin, Washington, DC, USA
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