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Implantable Sensor Sniffs Out Possible Signals of Osteoarthritis


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Said Lan Yin of China's Tsinghua University, “The limited surface area made it challenging to simultaneously attain both high sensitivity and high spatial resolution."

Credit: Shangbin Liu/Penn State/Tsinghua University

A flexible biosensor was developed by researchers at Pennsylvania State University (Penn State) and several universities in China to perform continuous, wireless monitoring of nitric oxide, a biomarker associated with inflammation, in rabbits.

The device is comprised of flexible and biocompatible organic electrochemical transistors and a channel made of the polymer PEDOT:PSS.

The sensor can transmit nitric oxide levels to a smartphone app via Bluetooth.

Penn State's Huanyu "Larry" Cheng said, "The reference-free sensor with a miniaturized active sensing region enables nitric oxide detection with improved spatial resolution compared with previously reported electrochemical nitric oxide sensors, which could allow the mapping of electrochemical signals to offer comprehensive diagnostic information."

From Pennsylvania State University
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Abstracts Copyright © 2022 SmithBucklin, Washington, DC, USA


 

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